Biotech startups are known for providing better diagnosis, high-quality drugs, and making medicine at affordable prices.

And the main aim of biotech startups is to develop health awareness and upgrade healthcare services.

Amid the Covid-19 pandemic, the biotech industry is one of the sectors that has gained significant growth.

Because apart from prescribed medicine, everyone is looking for other supplements and vitamins.

This has enabled the budding biotech startups in the US and all across the world to take off and flourish.

According to a report, around 3.060 biotech startups were founded in the last 5 years. 

But do you know the top 10 biotech startups in USA 2025? 

Here we have handpicked the best biotech startups based on a data-driven scouting approach, including many factors such as location, founding year, and relevance of technology.

Hence, if you are looking for up-to-date biotech solutions for your R&D, product development department, and innovation units, then here is the exclusive list of the top 10 biotech startups USA to watch in 2025. Let’s get to know these biotech startups in a little bit more detail.

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Top 10 Biotech Startups in USA to watch in 2025

BIOMILQ

Year Founded: 2020

Location: Durham, North Carolina

Website : https://www.biomilq.com/

BIOMILQ is one of the best biotech startups in the US working on cultured milk.

It is a women-owned, science-led, and mother-centred startup that is creating a better nutrition alternative for infants.

Moreover, this startup is working on a range of alternatives such as plant-based & culture alternatives.

And their patent-pending process involves the use of mammary cells from expectant mothers.

The core aim of this biotech startup is to provide a comprehensive and sustainable breastmilk alternative for infants.

Auxilius

Year Founded: 2020

Location: New York, United States

Website : https://www.auxili.us/

Auxilius is another US-based startup that develops a data-driven clinical trial financial management platform for biotech companies.

Many CROS don’t have any formal method to assess the risk associated with the budget. And eventually, it leads to failed drug trials and the loss of an enormous amount of money.

Hence, this clinical trial financial management platform performs proactive scenario modelling to adjust the timeline and cost limits during drug trials.

It also helps biotech companies ensure that the business prospects meet the budgets, contract terms, and milestones.

Kumuda

Year Founded: 2020

Location: Massachusetts, United States

Website : https://kumudarx.com/general-2

Recent advancement in AI enables biotech startups to leverage a large amount of chemical data for data-driven drug discovery.

And Kumuda is one of the US-based startups that is accelerating the discovery process of small molecule drugs.

By using this platform, the startup is unlocking novel drug targets for challenging diseases such as Covid-19.

This platform easily identifies the potent inhibitor drug candidate for Covid-19 and blocks the human ACE2 receptor to prevent the entry of the SARS-Cov2 Virus.

Curative

Year Founded: 2020

Location: California, United States

Website : https://curative.com/

This is one of the prominent biotech startups that provide the Covid-19 testing solution. It offers a range of solutions such as identify & isolate the infected individuals and preventing the outbreak of disease.

And it also provides different test uses such as quantitative PCR & antibody testing to detect the virus at an early stage.

Besides, the Curative’s swab test is FDA authorized, painless & self-administered.

The swab test just takes 20 seconds and the startup delivers the results in 2 days via email or text. 

Adnexi

Year Founded: 2020

Location: California, United States

Website : https://www.adnexi.com/pro

Adnexi is an efficient biotech startup that built PRO modules to strengthen the treatment and drug developers with disease intelligence information.

With disease intelligence, it gets easier for startups to identify & track infectious diseases to control them.

Moreover, this platform discovers the patent advocacy groups and connects these stakeholders to the drug discovery process.

Besides, this platform also maintains the track record of the treatment ecosystem and organization developing drugs. 

Nuvation Bio

Year Founded: 2019

Location: New York, United States

Website : https://www.nuvationbio.com/
Nuvation Bio is a biotech startup driven by science and focused on life.

The core aim of this biotech startup is to treat the patients with the most difficult to treat cancer for which all conventional methods are failed.

Besides, this startup is also venturing to develop a new generation of oncologist medicine that could improve patient lives by limiting the efficacy of current therapies with reduced side effects. 

Sana Biotechnology

Year Founded: 2020

Location: Seattle, WA

Website : https://www.nuvationbio.com/

Sana biotechnology is one of the prominent biotech startups that is involved in drug discovery and development within its core platform.

The core aim of this biotech startup is to modulate genes and replace the damaged genes in the body.

Moreover, this startup is also involved in gene delivering immunology, stem cell biology, and gene modification.

With scalable manufacturing, this biotech startup is aligned to work with the key stakeholders, for better patient access to their therapies. 

EQRX

Year Founded:

Location: Cambridge, MA

Website :  https://www.eqrx.com/

EQRX is a biotech startup that is working on one of the biggest healthcare challenges of our time.

And that is high-priced medicine. This biotech startup aims to offer affordable medicine to those who need them.

Besides, the company is focusing on proving medicine for oncology, immuno-inflammation, and rare diseases.

Along with this, EQRX has the right to develop and commercialize its services outside of its location. 

Arsenal Bio

Year Founded: 2019

Location: South San Francisco, CA

Website : https://www.arsenalbio.com/

Arsenal Bio is a US-based startup that focuses on building a programmable cell therapy by integrating technologies such as CRISPR-based genome engineering, synthetic biology, and machine learning with high throughput target identification.

Earlier, the company primarily focused on cancer treatment only but now it’s commercializing curative immune cell therapies. 

Trimuvira Immunologics Inc.

Year Founded: 2020

Location: Crystal Mountain Barton Creek, TX

Website : https://triumvira.com/

The main aim of this start-up is to focus on improving the lives of patients. Grounded by a deep understanding of immunology this startup is committed to identify, develop, and commercialize innovative therapies to strengthen the immune system of the body.

Besides, the company is also focusing on T-cell antigen coupler, a hybrid molecule consisting of multiple proteins domain to combine tumour-targeting abilities with T cell’s activation machinery.